A team of Indian and American researchers has identified immune-modulatory function of a protein that could potentially help in treating sepsis and other inflammatory diseases caused due to abnormal functioning of immune cells.
The protein, Fibulin 7 or Fbln7, is part of a group of glycoproteins often associated with elastic fibers and basement membranes which line tissues, blood vessels and other matrices. It is found in developing tooth, functioning as a cell adhesion molecule. It has ability to interact with other matrix proteins, receptors, and growth factors. It is also expressed in eye tissues and placenta. However, its functional significance was not known so far